Actividad cortical durante la estimulación olfativa en SQM

[elipoarch]

Este interesante estudio en fase I investiga las diferencias en el consumo de glucosa en el cerebro durante la estumulación olfativa en sujetos afectados con Sensibilidad Química Múltiple y un grupo de controles sanos. Para ello, realizan un escáner PET tras una estimulación olfativa neutral y otro tras una estimulación olfativa pura.
Llega a la conclusión de que la actividad cortical en enfermos de Sensibilidad Química Múltiple es diferente a la observada en los controles sanos.

Parece que los italianos se han propuesto demostrar que se puede diagnosticar la SQM mediante pruebas de imagen, no es la primera vez que realizan estudios de este tipo... ojalá cunda el ejemplo.

[t]Cortical activity during olfactory stimulation in multiple chemical sensitivity: a (18)F-FDG PET/CT study.[/t]
Chiaravalloti A1, Pagani M, Micarelli A, Di Pietro B, Genovesi G, Alessandrini M, Schillaci O.

Abstract

PURPOSE:
To investigate the differences in brain glucose consumption during olfactory stimulation between subjects affected by multiple chemical sensitivity (MCS) and a group of healthy individuals.

METHODS:
Two (18)F-FDG PET/CT scans were performed in 26 subjects (6 men and 20 women; mean age 46.7 ± 11 years) with a clinical diagnosis of MCS and in 11 healthy controls (6 women and 5 men; mean age 45.7 ± 11 years), the first scan after a neutral olfactory stimulation (NS) and the second after a pure olfactory stimulation (OS). Differences in (18)F-FDG uptake were analysed by statistical parametric mapping (SPM2).

RESULTS:
In controls OS led to an increase in glucose consumption in BA 18 and 19 and a reduction in glucose metabolism in BA 10, 11, 32 and 47. In MCS subjects, OS led to an increase in glucose consumption in BA 20, 23, 18 and 37 and a reduction in glucose metabolism in BA 8, 9 and 10.

CONCLUSION:
The results of our study suggest that cortical activity in subjects with MCS differs from that in healthy individuals during olfactory stimulation.

enlace: http://www.ncbi.nlm.nih.gov/pubmed/25690545" onclick="window.open(this.href);return false;

[lotto1]

Es que no es tan difícil. A mí se me paraliza. Espero que en España tengan la misma iniciativa